OK I've done some testing. For those of you having these problem on WXP and ATI Mobility Radeon disabling Catalyst A.I (and power management) seems to help on both patched and unpached version of Spore. On unpatched I've been able to run spore without crasing for long hours. Once I've patched Spore it freezes on evolution steps (e.g. cell->creature, creature-tribe). so remember to save prior to evolving and than after a while on the new EVO step. Once loaded in the "new" EVO step it runs.
hope this helps
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